We believe that to treat cardiomyopathies you have to understand the root cause. We’re focused on restoring cardiac contractility by targeting the key proteins that drive sarcomeric function.
The sarcomere is the basic contractile unit within muscle fibers, made up of thick and thin protein filaments that slide past one another. Within the sarcomere, myosin (the motor protein attached to the thick filament) binds to actin (a protein bound to the thin filament), forming cross-bridges that regulate the contraction and relaxation of the heart in a tightly regulated cycle. Thousands of sarcomeres acting in concert provide the ensemble force for muscle contraction.

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proteins

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